OpenSPR-XT
Maximize your productivity with fully automated, 24/7 operation of our benchtop SPR.
Description
OpenSPR-XT is built with our cutting-edge and affordable nanotechnology biosensor platform. It has been seamlessly integrated with our robust autosampler system to allow for fully automated, 24/7 operation.
Compatible Molecules:
- Proteins
- Peptides
- Antibodies
- Antibody variants
- Nucleic acids
- Lipids
- Adeno-associated viruses (AAV)
- Virus-like particles (VLPs)
- Hormones/cytokines
- Small molecules (application dependent)
Supported Assays:
- Kinetics/affinity characterization
- Kinetics/affinity screening
- Concentration analysis
- Yes/No binding
- Competition assays
- Epitope mapping
Technical Specifications
| Hardware | |
|---|---|
| Number of Channels | 2 |
| Flow Rate | 5–200 μL/min |
| Injection | Automated |
| Injection Volume | 100 μL |
| Sample Volume | 200 μL |
| Sample Capacity | 2x 96 well plates |
| Sample Temperature | Cooled from 22°C-4°C |
| Unattended Run Time | 24 hours |
| Temperature Range | 4°C – 40°C (lower limit 10°C below ambient temperature) |
| Temperature Precision | +/- 0.25°C |
| Buffer Switching | 3 ports available, automated switching |
| Instrument Size | 78 x 57.5 x 36 cm (OpenSPR with XT autosampler) |
| Weight | 17 kg (OpenSPR), 21 kg (autosampler) |
| File Output | CSV, TXT compatible with TraceDrawer |
| Performance | |
|---|---|
| Association Rate (kon) | 1×103–1×107 1/M*s |
| Dissociation Rate (koff) | 0.1–1×10-5 1/s |
| Affinity Range (KD) | mM-pM |
